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The GLP-1 RAs that are similar to exendin-4 (Exenatide and Lixisenatide) are eliminated by the kidneys and therefore in patients with severe renal disease these drugs are contraindicated (22)

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Contact your GP or NHS 111 if diarrhoea persists beyond 7 days despite dietary modifications, if you experience signs of dehydration, or if symptoms significantly impact your quality of life

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doi: 10.1002/acr2.70103

However, these are relatively minor gaps in the context of FuturHealths overall offering