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In many cases, this change is temporary and improves as the body adjusts to the medication

Weight loss typically accelerates once maintenance dose is reached and continues for 12-18 months before stabilizing
Feb 22, 2026 You are sitting at the highest dose of tirzepatide

But when heartburn is moderate to severe, PPIs and H2 blockers are dramatically more effective than any supplement or home remedy

Chronic weight management typically requires long-term therapy, making ongoing safety monitoring important

This lack of human data makes it difficult to say with certainty what the risks are
