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The most frequent serious adverse events were infections and cardiac- and kidney-related disorders

The current product labels recommend stopping GLP-1 medications at least 2 months before pregnancy

Biological Explanations and Clinical Implications These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones, says Jena Shaw Tronieri, Senior Research Investigator at Penns Center for Weight and Eating Disorders and a co-author of the study

Patients should be alert for signs of antibiotic-associated diarrhoea, particularly diarrhoea containing blood or mucus, or accompanied by severe abdominal cramping, which could indicate Clostridioides difficile infection requiring urgent medical attention