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who discovered glp 1 agonists should win a Nobel for the science of the Ozempic revolution? @nejm correct today’s review of
Description
Saxagliptin is not recommended in patients with ESRD, while alogliptin and sitagliptin can be used at doses of 6.25 mg and 25 mg respectively
7 If an SGLT-2 inhibitor cannot be taken due to a contraindication to therapy, drug intolerance, or insufficient kidney function, the ADA recommends the addition of a GLP-1 RA ( Figure 2 )

PMID: 38351702

L., Chan J

in ELIXA, also hospital admission for unstable angina)

Compared with patients without diabetes, patients with diabetes have a 2fourfold higher risk of atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease, stroke, and peripheral artery disease [1]