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The qualifying diagnoses (HFpEF, uncontrolled hypertension, CKD, pre-diabetes, prior MI, prior stroke, PAD) are the conditions where GLP-1 trials have shown direct benefit or strong biological plausibility for benefit

OConnor, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Instead, the arrival of oral GLP-1s is likely to attract needle-hesitant patients, effectively expanding the total addressable market (TAM) rather than displacing the existing one

For full prescribing details, refer to the electronic Medicines Compendium (eMC) Summary of Product Characteristics (SmPC) for each agent

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The goal is to find the approach that best matches the patient and whats driving their weight. For some patients, medication may be enough to reach and maintain their goals