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Tirzepatide initiation begins at 2.5mg weekly, increasing in 2.5mg increments every four weeks to a maintenance dose of 515mg 6

Berberine can cause digestive issues like diarrhoea, constipation, excess gas, and an upset stomach

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When butyrate binds to free fatty acid receptor 2 (FFAR2) and free fatty acid receptor 3 (FFAR3) on intestinal L cells, it stimulates GLP-1 release
