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Conclusions and Implications The established 3D imaging and quantification approach provides a powerful tool for evaluating the therapeutic efficacy of antifibrotic compounds and studying the cellular and pathological mechanisms underlying cardiovascular diseases

semaglutide 0.5 mg (n=12), 1.0 mg (n=12), or placebo (n=12)

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Neoepitopes were identified in DS and DP semaglutide follow-ons, indicating potential immunogenicity