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Electrolyte loss: Vomiting or diarrhea can lead to electrolyte loss
HARMONY or discord in cardiovascular outcome trials of GLP-1 receptor agonists

Sarcopenic obesity, which combines obesity and sarcopenia, is concerning and is associated with reduced quality of life and elevated risk of falls, cardiovascular disease, and mortality

Obesity, type 2 diabetes mellitus and cardiovascular disease risk: an uptodate in the management of polycystic ovary syndrome

This is likely the biggest factor in inducing weight loss

Reporting bias arises from disproportionate U.S
