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Figures 6BE shows the IF results demonstrating the upregulation of CGA on the expression levels of mitophagy markers PINK1 and Parkin in myocardial tissue

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Semaglutide is a similarly derived GLP-1RA agent with the advantage of weekly administration and was more effective than liraglutide in a head-to-head trial (16.3% vs 7.8% change in body weight) [102]

Clinical trials have demonstrated that Mounjaro can lead to significant reductions in HbA1c levels (a measure of long-term blood glucose control) and substantial weight loss

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