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[DOI] [PubMed] [Google Scholar] [27].Zhu DD, Zhang XP, Zhang BL, Hao YY, Guo XD, Safety Assessment of Microneedle Technology for Transdermal Drug Delivery: A Review, Advanced Therapeutics 3(8) (2020) 2000033
Achieving sustained in vivo production of Exe4 could offer a lasting defense against a range of complex metabolic diseases
10 The design logic was therefore explicit: reproduce the pharmacology of an injectable peptide agonist in a molecule small and stable enough to survive the gut and be swallowed as a daily pill
FDA approved Ozempic in December 2017 as an adjunct to diet and exercise for improving glycemic control in T2D
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