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For a patient on metformin and insulin degludec who cannot use GLP-1 receptor agonists due to pancreatitis history, add an SGLT2 inhibitor with proven cardio...

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Notably, GLP-1RAs benefit pain management through their neuroprotective and metabolic regulatory properties, such as inhibiting inflammation responses and oxidative stress, promoting -endorphin release and modulating several other crucial biological pathways