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Kellerer, M., Kaltoft, M

Results from the TRIUMPH-4 trial, published in December 2025, showed participants with obesity and knee osteoarthritis taking retatrutide 12mg lost an average of 28.7% of their body weight at 68 weeks

The concern is during induction of anesthesia, patients could have significant food or liquids in the stomach due to gastroparesis

Summary GLP-1 medications create wildly different outcomes depending on how patients manage details between doses, according to HealthVerity Blog's 2025 analysis of real-world data

He points to a clinical trial published in The New England Journal of Medicine studying the impact of semaglutide in people who were diagnosed with both overweight or obesity and heart disease, but who had no history of diabetes

Try to carry around a water bottle to drink consistently throughout the day