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Interestingly, a post-hoc analysis of the Prediabetes Lifestyle Intervention Study (PLIS) suggested that patients achieving prediabetes remission differed from non-responders in improvement in whole body insulin sensitivity, visceral adipose tissue (VAT) and intrahepatic fat rather than insulin secretion upon a similar weight loss 76

Sehgal P et al

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Multivariate and univariate analysis of body weight at 3 and 9 months demonstrated no significant difference between groups (Supplementary Table 6.1, Supplementary Table 6.3, Table 2)

To view or add a comment, sign in As more patients turn to GLP-1 medications for weight management, were seeing increased cases of nutrient depletion especially in B-vitamins, choline, and amino acids

The Gut-Inflammation Connection and GLP-1 Therapy Your gut lining acts as a selective barrier, allowing nutrients in while keeping harmful bacteria and toxins out