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Understanding why provider guidance matters helps patients access these medications responsibly through appropriate channels

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Three major studies recently published in The New England Journal of Medicine highlight progress with oral GLP-1 therapies.

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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1