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These effects typically peak within the first week and diminish as your body adapts, though some patients require dose adjustment or slower titration

These treatments work by tapping into your bodys natural systems to regulate appetite, metabolism, and fat storage

Scaling back training volume during this period while maintaining intensity (weight on the bar) preserves the muscle building stimulus without overreaching when recovery capacity may be temporarily compromised

If you're considering stopping treatment or switching medications, discussing the timeline with your prescriber helps set realistic expectations about when appetite and metabolism will normalize

and various long-acting GnRH agonists (Sartor, 2003)