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These compounds are commonly referenced in GLP-1 receptor and metabolic signaling research, where peptides are studied for their interaction with biological pathways related to energy regulation, endocrine signaling, and peptide receptor activity

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mean follow-up: 6.54 years)

Cryo-EM analysis of a complex involving an exendin-4 analogue, the GLP-1R and Gs protein revealed two receptor conformers with distinct modes of peptide-receptor engagement
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