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A major 2025 analysis published in JAMA Network Open followed more than 60,000 adults with obesity and type 2 diabetes

[ 1-3] While dietary and lifestyle changes can be effective in promoting ideal body weight, the reality is that in obesity, the use of diet and lifestyle alone produces poor results as only about 5-15% of these people will achieve a 20% loss in body weight and most regain that weight within a year of losing it

P., Zhang W., Bansback N., Amarsi Z., Birmingham C

These medications are clinically proven, require prescriptions, and are regulated to ensure patient safety

medRxiv [Preprint] 2024 Feb 18 2

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