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A structured narrative literature review was conducted by five authors using MEDLINE/PubMed as the primary database, covering publications in English from January 2005 to January 2025

Individual responses vary widely based on body composition, metabolism, and gastrointestinal sensitivity

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Effects of sodium-glucose linked transporter 2 inhibition with ertugliflozin on mitochondrial function, energetics, and metabolic gene expression in the presence and absence of diabetes mellitus in mice