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The ECL1 of all activated GLP-1R and GCGR structures consistently adopt -helical conformation bridging extended TM2 and TM3 helices by two short linkers to form extensive interactions with bound agonists
They had much more in common than they had in differences
3A, B to make differences easier to detect
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doi: 10.1038/s41422-020-0291-z 95 PedersenH
