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Those taking GLP1s are more likely to have T2D and hypertension, both risk factors for NAION

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Guirguis says combination treatments such as this could offer additive or synergistic effects meaning that patients have a better chance of responding to at least one of the mechanisms and could experience fewer GI side effects as a result of the dual approach

[ 2 ] Interestingly, a 2025 mouse study did test an experimental semaglutide patch and found it caused weight loss and boosted metabolism compared with injections

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