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Persistence should not be judged by staying on a single drug indefinitely, but by maintaining engagement in care and working with clinicians to find sustainable, effective treatment strategies over time. The researchers also visualized treatment pathways to illustrate how patients transitioned among medications during the study period

Tsuchida T, Friedman SL

Szklarczyk, D

Futhermore, 2025 results from the ATTAIN-MAINTAIN trial demonstrated orforgliprons ability to compete in the maintenance segment

For functional enrichment analysis, the R package gprofiler2 (v.0.2.0) was used to identify enriched functional terms (GO:MF, GO:BP, GO:CC, KEGG pathways and REACTOME pathways)

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