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Further study is needed to examine how these perceptions evolve over time

This local gut distribution of GLP-1 receptors supports a potential bidirectional interaction between GLP-1 signaling and the gut microbiota, which could potentially contribute to the therapeutic benefits observed

This gastric emptying effect may attenuate somewhat over time, though appetite suppression continues through multiple pathways

Lorza-Gil et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Sinclair AJ, Burdon MA, Nightingale PG, et al

3) [81], and the use of site-specific brain injections, together with chemogenetics targeting distinct GLP-1R+ populations, illustrates considerable redundancy in GLP-1R+ sites coupled to reduction of food intake