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In addition, some putative effects of GLP-1RAs on cognitive and mental health symptoms may not require direct activity in the CNS, but rather be mediated by the actions that these medications express in the periphery across immune, endocrinemetabolic and gutbrain axis mechanisms (Fig

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Semaglutide is a compounded medication used in weight loss treatments

While the risk of hypoglycemia is low with GLP-1 receptor agonists alone, this risk increases when combined with insulin or sulfonylureas

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