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The guidelines state, Anesthesiologists should recognize that these conditions can increase the likelihood of regurgitation and pulmonary aspiration and should modify these guidelines based upon their clinical judgment. A previous version states, The guidelines may not apply to, or may need to be modified for, patients with coexisting diseases or conditions that can affect gastric emptying or fluid volume (e.g., pregnancy, obesity, diabetes, hiatal hernia, gastroesophageal reflux disease, ileus or bowel obstruction, emergency care, or enteral tube feeding) and patients in whom airway management might be difficult. Requiring patients to abstain from food for longer than 8 hours, even if the optimal duration was unknown, would have been the most cautious approach, even if it was unenjoyable for patients

Investigation of combination therapies pairing incretin-based agents with other mechanistically distinct therapies may yield additive or synergistic benefits [71]

- WebMD, accessed April 22, 2025, Life After Wegovy and Zepbound - WebMD, accessed April 22, 2025, GLP-1 Diet: Foods to Eat and Avoid on Weight Loss Medication, accessed April 22, 2025, Avoid These Foods While Taking Ozempic, accessed April 22, 2025, Weight loss: New dietary guidelines for people taking Wegovy, Ozempic - Medical News Today, accessed April 22, 2025, What is Zepbound

What provides meaningful benefits for one person may offer minimal value for another, and there's no way to predict individual response without trying the product for an adequate assessment period

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