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reported that individuals with active BAT had lower prevalences of cardiometabolic diseases, and the presence of BAT was independently correlated with lower odds of type 2 diabetes, dyslipidemia, coronary artery disease, cerebrovascular disease, congestive heart failure and hypertension [71]
References: Wilding JPH, et al

Clinical oversight is provided by pharmacist independent prescribers rather than doctors
Gastrointestinal issues : Persistent nausea, vomiting, and diarrhea have been linked to the use of these medications

Of the nine patients, seven reported NAION-like symptoms

Observations of variable lean mass outcomes and dietary shifts during GLP-1RA therapy [40, 75] suggest that substrate availability may influence therapeutic durability even in the absence of overt deficiency