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The FDA approved sitagliptin, the first DPP-4i on the market, in 2006 and shortly after, numerous additional DPP-4i received market clearance

2024doi:10.1097/RHU.0000000000001949

It can also be significantly impacted by social, economic, and environmental challenges that individuals may face like limited health education, financial constraints, and lack of social support

infusion of hypertonic saline (5% NaCl) [755]

Tirzepatide is expected to register the highest CAGR of approximately 12.5% during 2026-2035
