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Description
Column: C18 150 4.6 mm 5 m Mobile phase: Water (0.1% TFA) / Acetonitrile (0.1% TFA) Gradient: 3565% ACN Flow rate: 1.0 mL/min Detection: UV 214 nm Injection volume: 10 L Run time: 15 minutes Application: Quantification and purity analysis of semaglutide in pharmaceutical formulations

semaglutide 0.5 mg (n=12), 1.0 mg (n=12), or placebo (n=12)
Background Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) reduce the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM)
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Stories about medicine safety in the U.S

A study of health insurance claims found a 44% reduction in hospitalizations for GLP-1 users
