glp-1 receptor agonists and cancer risk in adults with obesity GLP1 Agonists—Effects beyond Diabetes Weight Reduction with GLP-1 Agonists

GLP-1R analogs have been leveraged for their relatively selective modalities of action in pancreatic islets and the central nervous system to precisely deliver cargo such as antisense oligonucleotides and nuclear hormones to these tissues

[DOI] [PubMed] [Google Scholar] 941.Gault V.A., Bhat V.K., Irwin N., Flatt P.R

doi: 10.14218/JCTH.2024.00271, 23

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

The slightly higher side effect rate is a tradeoff for significantly better weight loss results

GLP-1 agonists and blood pressure: A review of the evidence