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In another report, a 26week treatment with the GLP1R/GIPR dual agonist LY3298176 (Tirzepatide, Eli Lilly), showed significant reduction in A1c in an incremental, dosedependent manner (4 doses from 1 mg to 15 mg, A1c reduction from 1.06% to 1.94% respectively)

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Mentre gli effetti positivi sul muscolo sarebbero direttamente legati al farmaco attraverso la sensibilit allinsulina, quelli secondari potenzialmente negativi sarebbero pi condizionati dal forte e rapido dimagrimento