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These include cases of pancreatitis and a potential association with thyroid C-cell tumors in rodent models

TABLE 3

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They reduce de novo lipogenesis by inhibiting transcription factor sterol regulatory element-binding protein 1c (SREBP-1c), which is a master regulator of fatty acid synthesis ( TABLE 1 Therapeutic actions of GLP-1 receptor agonists in liver disease: summary of experimental and clinical findings