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Description
It represents a different mechanistic approach than retatrutide, combining amylin and GLP-1 agonism rather than GLP-1, GIP, and glucagon agonism

After the first injection, tirzepatide levels gradually increase over several weeks
[DOI] [PubMed] [Google Scholar] 10.Lee YS, Jun HS

GLP-1 ,

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Tirzepatide for Metabolic DysfunctionAssociated Steatohepatitis with Liver Fibrosis