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No, it hasnt existed, said Dr

This rebound effect is one reason why weight loss medication is considered a long-term treatment rather than a temporary intervention

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As a GLP-1RA, semaglutide increases the secretion of insulin from pancreatic -cells and supresses glucagon release from pancreatic -cells

Evidence from two large, international phase 3 clinical trials, published in The Lancet Diabetes & Endocrinology , indicates that this higher dose may provide an important treatment alternative for people who have not achieved sufficient results with current therapies