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Funding Statement Special Clinical Specialty in Putuo District, Shanghai (2020tszk01, 2024tszk02), Scientific Research Project of Shanghai Municipal Health Commission (20204Y0154, 202240309), and Program of Xinglin Youqing in Putuo District (ptxlyq2302)

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Exendin-4 has been shown to act on the Wnt/-catenin pathway in osteoblasts via the GLP-1R, thereby promoting bone formation and reducing sclerostin levels in T2DM rats (Kim et al., 2013)

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NICE has recommended Wegovy (semaglutide) for reducing the risk of major adverse cardiovascular events in patients with existing cardiovascular disease who are overweight or obese

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Global News reports that this is the first GLP1 pill approved in Canada and that all other GLP1 therapies available in the country to date are injectables

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