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In a 4-year CV outcomes trial (Trial 7), cholelithiasis was reported in 1.1% of patients treated with RYBELSUS 14 mg and in 0.9% of placebo-treated patients

GLP-1RAs used for the treatment of type 2 diabetes was gradually expanded to other diseases, such as obesity [42], non-alcoholic fatty liver disease [43], and Alzheimers disease [44]

Age does not appear to meaningfully affect tirzepatide elimination
However, because they work similarly and have many of the same side effects, you may not notice any difference between them

Taylor SI
L.ZhongW.ShuJ.Abu MuchA.LotanD.GrupperA.et al (2021)
