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Seven trials were included for each incident SUD outcome (protocol 1), and one trial was included for adverse outcomes in people with preexisting SUD (protocol 2)
He L, Wang J, Ping F, Yang N, Huang J, Li W, et al
95% CI 2.3-3.4), reflecting serotonergic effects on platelet function
In the self-controlled case series design, use of GLP-1 RAs was associated with a lower incidence rate ratio (IRR) of suicide or suicide attempts one year after treatment initiation (IRR: 0.45
doi: 10.1210/en.2012-1595 92 XieCWangXYoungRLHorowitzMRaynerCKWuT
Intriguingly, beyond their metabolic benefits, GLP-1RAs also exhibit anti-inflammatory effects
