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Semaglutide can potentially cause urinary difficulties in some patients, although the evidence is limited and mostly anecdotal, with no direct studies assess...

We used version 2 of the Cochrane risk-of-bias tool for randomised trials to assess risk of bias for the primary outcome

In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

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Researchers continue to study its molecular characteristics, peptide structure and biochemical behaviour using validated laboratory techniques and analytical methods

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