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Among-group and intra-group data comparisons were performed with the ANOVA and Students t -tests

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Male C57BL/6J mice were anaesthetized with i.p

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In the ongoing SURPASS-CVOT trial, the safety of tirzepatide versus dulaglutide is being assessed in patients living with T2DM with confirmed atherosclerotic CVD and is to be completed by 2025 (ClinicalTrials.gov ID NCT04255433)

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preparation, review, or approval of the manuscript

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