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Side effects by dose A meta-analysis of 10 trials (6,836 participants) found total GI event rates of 39% at 5 mg, 46% at 10 mg, and 49% at 15 mg

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Indirect effects via cardiometabolic risk reduction may be more plausible than direct neuroprotective effects at present

57 The confirmatory secondary endpoints analysis included a composite HF endpoint of death from cardiovascular causes or hospitalisation/urgent visit for HF

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