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Risk-benefit implications With increasing prevalence of GLP-1 agonists in our perioperative population and emerging reports of retained gastric content despite recommended fasting guidelines, a review on the perioperative handling of GLP-1 agonists and assessment of these patients are warranted to balance their cardiometabolic benefits and unquantified risk of catastrophic pulmonary aspiration

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Patients with chronic kidney and cardiovascular diseases have a higher risk of fatality, especially if the water retention symptoms are significantly high or have worsened
