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GLP-1s help to stimulate insulin release and reduce glucagon production

Its safe for long-term use under medical supervision

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Specific expression of GLP-1R on the spinal dorsal horn microglia was found, and the efficacy as well as potency of GLP-1, exenatide, and geniposide on antinociception in a variety of animal models of pain hypersensitivity versus acute nociceptive responses were evaluated (Gong et al., 2014b)

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The BCPNN analysis further validated these findings, demonstrating that female patients had higher risks of long-term treatment-related adverse reactions, whereas male patients experienced more acute adverse events in the short term