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GLP-1 therapies have demonstrated substantial weight-reduction benefits, with studies showing an average weight loss of 4.6 kg, a BMI reduction of 2.1 kg/m, and a decrease in waist circumference of 4.6 cm compared to placebo

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GLP-1 & Muscle Loss: Evidence and Prevention GLP-1 receptor agonists such as semaglutide and liraglutide have transformed weight management for people with obesity, but concerns about muscle loss during treatment are increasingly common

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