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Shatha Taha, GP practitioner specialising in longevity and wellness

Follistatin is a protein that binds to MSTN and activin, thereby preventing these ligands from interacting with their receptors, ActRIIA/B.[13] This property has been utilized in gene therapy to treat degenerative muscle diseases.[84] The application of this therapy is not limited to muscle-related diseases

Huang Z, et al

That is a rare combination, and it is why rheumatologists are paying attention even though no randomized controlled trials specifically evaluating tirzepatide for autoimmune conditions exist yet

These peptides were designed to mimic the action of these hormones (what in pharmacology is called an agonist effect) on the control of glycemia

J Cereb Blood Flow Metab (2011) 31(8):1696705