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Docusate sodium (Colace) at 100 to 200 mg twice daily helps soften existing hard stool

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In particular, the incidence of MACE was significantly lower in the GLP-1RAs group

Whilst most patients tolerate the medication well, skin reactions can occasionally occur at the injection site or more widely across the body

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Common side effects (nausea, constipation) typically resolve within 2-3 weeks