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In the SURPASS tirzepatide clinical trials, injection-site reactions including bruising occurred in fewer than 5% of participants

Reviews suggest that troches and ODTs may be more convenient than liquid drops (no measuring, no dripping) but do not offer meaningfully different effectiveness

This reduces the risk of hypoglycemia compared to insulin or sulfonylureas, though the risk increases when used with these medications

From changing your diet and movement routine to handling the side effects, youve definitely earned it

They are developed and are manufactured by different companies

The most common TEAEs with orforglipron were GI in nature (nausea 34%, constipation 25%, diarrhea 23%, vomiting 24% [all reported with 36 mg dose]) and were usually mild to moderate in severity