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For athletes who genuinely need weight loss for health reasons, these medications can be effective when combined with appropriate exercise and nutrition strategies

Quick Answer: Clinically diagnosed gastroparesis in GLP-1 receptor agonist users appears uncommon, though precise incidence rates remain uncertain due to methodologic challenges in distinguishing expected gastric emptying delay from pathologic gastroparesis

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Last reviewed: July 7, 2026 Last updated: July 7, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

This contrasts sharply with prescription GLP-1 agonists, which demonstrate 10-22 percent average weight loss in Phase 3 randomized controlled trials

Rosenstock J, Hsia S, Nevarez Ruiz L, Eyde S, Cox D, Wu W-S, et al