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Description
Dramatic changes in thiopurine metabolite levels in a patient with inflammatory bowel disease treated with tirzepatide for weight loss

Contact: Brandyn Bissinger [email protected] Photos accompanying this announcement are available at:

Many people begin to experience reduced appetite and improved portion control early on, while more significant weight loss generally occurs over several months

Appendix Abbreviations AE(s): Adverse Event(s) BMI Body Mass Index CENTRAL Cochrane Central Register of Controlled Trials CI Confidence Interval CSF Cerebrospinal Fluid GLP-1 Glucagon-Like Peptide-1 GLP-1 RA(s) GLP-1 Receptor Agonist(s) I (Statistical measure of heterogeneity) ICP Intracranial Pressure IIH Idiopathic Intracranial Hypertension IQR Interquartile Ranges logMAR Logarithm of the Minimum Angle of Resolution MD Mean Difference NOS Newcastle-Ottawa Quality Assessment Scale PICO Population, Intervention, Comparison, and Outcomes PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses PROSPERO (International prospective register of systematic reviews Name, not an acronym defined in text) RCT(s) Randomized Controlled Trial(s) RoB2 Revised Cochrane risk-of-bias tool (for randomized trials) RR Risk Ratio SD Standard Deviation SMD Standardized Mean Difference ULN Upper Limit of Normal VRS Verbal Rating Scale WOS/WoS Web of Science Footnotes ORCID iDs: Jamal Ahmad Ahmed Mohamed Hamdy Bahaa Elfakharany Muhammad M

New cases are being added steadily as more and more patients are experiencing the disadvantages of using GLP-1 drugs to lose weight

Certain medicines including corticosteroids, some antidepressants (such as mirtazapine), and antipsychotics are associated with weight gain and may partially offset the benefits of retatrutide (BNF
