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Tirzepatide (Mounjaro for diabetes and Zepbound for obesity, both Eli Lilly), a dual GLP-1/GIP agonist titrated gradually across a broad dosing range, showed a favorable safety profile, with GIP agonism probably buffering GLP-1-mediated fluid shifts, stabilizing vascular tone and reducing ischemic vulnerability

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For more information on mild side effects of either drug, see the prescribing information for Ozempic and Victoza

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