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Mike Haney: I think that's a great place to wrap it up

Even if you were on high-dose tirzepatide, the semaglutide-specific side effect profile requires independent titration

Chest pain , severe shortness of breath, or new irregular heartbeat symptoms

The authors also wrote that their analysis of progression to wet AMD may have been underpowered due to the substantially smaller cohort size

Instead, it supports reimbursement

Atherosclerosis and GLP-1RA The clinical trials investigating the impact of GLP-1RA on cardiovascular health have shown that the incidence of MACE does not differ between the GLP-1R agonist and placebo groups until 1218 months after initiation of therapy, which aligns with the potential anti-atherogenic effect of GLP-1RA (Sattar et al