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Description
in vitro cell culture experiments (Owen et al., 2000

ER: extended release
doi:10.1016/s0140-6736(13)60647-9

So when someone asks whether "Omzo works," they're really asking two different things - and the answers are different

Most of the GIP receptor targeting compounds are evaluated in vitro as stimulators of a single cellular pathway, which is the Gs-mediated cAMP production (30, 37)

Patients with low GLP1R activity often respond better to tirzepatide (which activates GIP pathways), while others benefit more from semaglutide