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Introduction Embarking on a weight loss journey can be daunting, and trust me, I've started and restarted countless times

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After age 50, maintaining muscle becomes increasingly challenging as the body becomes less efficient at building new tissue in response to protein and exercise

Transitioning off tirzepatide When the time comes to discontinue tirzepatide, whether because you have reached your goal weight or for another reason, the long half-life means the drug does not leave your system overnight

Recommendations are to avoid tirzepatide during pregnancy, discontinuing it before conception unless the potential maternal benefit clearly outweighs the potential foetal risk, due to animal studies showing foetal growth restriction and developmental abnormalities at clinically relevant exposures